PEOPLE

BENJAMIN ALPER

Assistant Professor - Department of Chemistry and Physics, Sacred Heart University

Ph.D.: Biochemistry and Molecular Biology, University of Georgia, Athens GA (Walter K. Schmidt Jr., advisor)

Post-doctoral: Biochemistry, St. Jude Children's Research Hospital, Memphis TN (Janet Partridge, advisor)

BLAIR YESKO

Undergraduate Student Researcher

Blair is a rising Senior in Sacred Heart University's Chemistry Major (c/o 2019) electing concentration in molecular biochemistry, and also plays attack for the SHU lacrosse team.

Blair is exploring the mechanistic function of human insulin-degrading enzyme, by investigating structure/function relationships that may be critical to enzyme function. She is currently working to clone, purify and characterize engineered mutant alleles of the insulin-degrading enzyme that she designed as part of the second semester CH344 (Biochemistry II Lab) curriculum.

BRETT MAGNUS

Undergraduate Student Researcher

Brett is a rising senior in Sacred Heart University's first class of biochemistry majors (B.S. biochemistry c/o 2019), and also plays goalie for the SHU hockey team.

Brett is studying mechanistic implications of targeted insulin-degrading enzyme mutants that he cloned and purified as part of the second semester biochemistry lab.

NICHOLAS FUSCO

Undergraduate Student Researcher

Nick is a rising senior in Sacred Heart University's first class of biochemistry majors (BS in Biochemistry, c/o 2019), and serves as a Research Associate at St. Vincent's Medical Center and plays alto saxophone in the Sacred Heart University Band.


Nick is exploring the use of magnetically active nanoparticles for the targeted manipulation of amyloidogenic peptides, in collaboration with researchers from the labs of Jillian Smith-Carpenter (Fairfield University) and Olin Thompson Mefford III (Clemson University).

Nick's work has been supported by the SHU College of Arts and Sciences Undergraduate Research Initiative, which awarded funding for his research and travel to present at the 255th National Meeting and Exposition of the American Chemical Society in New Orleans LA (March 2018). Nick has also presented his work at the Sacred Heart University Academic Festival and is a coauothor on an a scientific manuscript under  review for publication in the ACS journal Biochemistry.

ANDREA SIDOR

Masters Student Researcher

Andrea is a Master's student in the department of Chemistry studying towards the combined BS/MS (4+1) in Chemistry with concentration in molecular biochemistry. From 2014-2017 Andrea was also a clutch infielder for SHU softball team.

Andrea's master's thesis concerns structure function studies of the human insulin degrading enzyme, emphasizing characterization of charge sharing interactions between enzymatic domains. Andrea was also involved in the development of enzyme kinetic assays for analysis of mammalian arginase function, and conducted pilot screens for identification of putative arginase inhibitors.

MARYAM KALHAMDI

Masters Student Researcher

Maryam is a Master's student in the department of Chemistry studying towards the MS in Chemistry with concentration in molecular biochemistry. 

Maryam is working in collaboration with researchers from the labs of departmental colleagues Dr. Joe Audie and Dr. Todd Sullivan to identify and characterize novel inhibitors of human arginase 1, a potential anticancer target.

PEOPLE

BENJAMIN ALPER

Assistant Professor - Department of Chemistry and Physics, Sacred Heart University

Ph.D.: Biochemistry and Molecular Biology, University of Georgia, Athens GA (Walter K. Schmidt Jr., advisor)

Post-doctoral: Biochemistry, St. Jude Children's Research Hospital, Memphis TN (Janet Partridge, advisor)

BLAIR YESKO

Undergraduate Student Researcher

Blair is a rising Senior in Sacred Heart University's Chemistry Major (c/o 2019) electing concentration in molecular biochemistry, and also plays attack for the SHU lacrosse team.

Blair is exploring the mechanistic function of human insulin-degrading enzyme, by investigating structure/function relationships that may be critical to enzyme function. She is currently working to clone, purify and characterize engineered mutant alleles of the insulin-degrading enzyme that she designed as part of the second semester CH344 (Biochemistry II Lab) curriculum.

BRETT MAGNUS

Undergraduate Student Researcher

Brett is a rising senior in Sacred Heart University's first class of biochemistry majors (B.S. biochemistry c/o 2019), and also plays goalie for the SHU hockey team.

Brett is studying mechanistic implications of targeted insulin-degrading enzyme mutants that he cloned and purified as part of the second semester biochemistry lab.

NICHOLAS FUSCO

Undergraduate Student Researcher

Nick is a rising senior in Sacred Heart University's first class of biochemistry majors (BS in Biochemistry, c/o 2019), and serves as a Research Associate at St. Vincent's Medical Center and plays alto saxophone in the Sacred Heart University Band.


Nick is exploring the use of magnetically active nanoparticles for the targeted manipulation of amyloidogenic peptides, in collaboration with researchers from the labs of Jillian Smith-Carpenter (Fairfield University) and Olin Thompson Mefford III (Clemson University).

Nick's work has been supported by the SHU College of Arts and Sciences Undergraduate Research Initiative, which awarded funding for his research and travel to present at the 255th National Meeting and Exposition of the American Chemical Society in New Orleans LA (March 2018). Nick has also presented his work at the Sacred Heart University Academic Festival and is a coauothor on an a scientific manuscript under  review for publication in the ACS journal Biochemistry.

ANDREA SIDOR

Masters Student Researcher

Andrea is a Master's student in the department of Chemistry studying towards the combined BS/MS (4+1) in Chemistry with concentration in molecular biochemistry. From 2014-2017 Andrea was also a clutch infielder for SHU softball team.

Andrea's master's thesis concerns structure function studies of the human insulin degrading enzyme, emphasizing characterization of charge sharing interactions between enzymatic domains. Andrea was also involved in the development of enzyme kinetic assays for analysis of mammalian arginase function, and conducted pilot screens for identification of putative arginase inhibitors.

MARYAM KHALHAMDI

Masters Student Researcher

Maryam is a Master's student in the department of Chemistry studying towards the MS in Chemistry with concentration in molecular biochemistry. 

Maryam is working in collaboration with researchers from the labs of departmental colleagues Dr. Joe Audie and Dr. Todd Sullivan to identify and characterize novel inhibitors of human arginase 1, a potential anticancer target.

PEOPLE

ACTIVE LAB MEMBERS

LAB ALUMNI

PHIL GELINEAU

M.S. Chemistry, December 2017

Thesis: Quantitative detection of free proline as a marker for haze stability in beer

(Manuscript in preparation for submission to the Journal of the American Society of Brewing Chemists)

Liquid manager, innovation R&D at Diageo Inc., Norwalk CT

LAZAROS STEFANIDIS

M.S. Chemistry, August 2017

Thesis: Kinetic studies of glutathione S-transferase

Publications:

Bisubstrate kinetics of glutathione S-transferase: a colorimetric experiment for the introductory biochemistry laboratory. Stefanidis L, Scinto K, Strada MI, Alper BJ.

2018. Journal of Chemical Education. 95(1):146-151

Efficient synthesis of α-fluoromethylhistidine di-hydrochloride and demonstration of its efficacy as a glutathione S-transferase inhibitor. Considine KL, Stefanidis L, Grozinger KG, Audie J, Alper BJ.  2017. Bioorganic and Medicinal Chemistry Letters. 27(6):1335-1340

(Other manuscripts in preparation)

Lazaros is applying for Ph.D. fellowships in biochemistry or molecular life sciences

KRYSTAL SCINTO

B.S. Chemistry, 2015

Krystal developed and implemented of a colorimetric method for evaluating function of glutathione S transferases for use in the biochemistry lab.  Krystal presented her work at the 249th National Meeting of the American Chemical Society, and along with her colleague Khristopher White also presented this work at the 2015 Sacred Heart University Academic Festival. Krystal continued to develop this research, which  was later reported in the Journal of Chemical Education.

After graduating, Krystal began her studies of pharmacy at the University of Connecticut. Krystal is a Pharm. D candidate (2020) and recently accepted a position at the Hospital of Central Connecticut (New Britain) as a Medication History Technician.

NOELLE BIANCULLI

B.S. Chemistry, 2016

Noelle adapted a colorimetric assay for human arginase activity for use in the lab and served as Captain of the Sacred Heart University equestrian team

Noelle presented her research at the 2016 Sacred Heart University Academic Festival.

After graduating, Noelle began her studies of pharmacy at the University of St. Joseph, in West Hartford, CT

KHRISTOPHER WHITE

B.S. Chemistry 2015

Khristopher co-developed and co-implemented a colorimetric method for evaluating function of glutathione S-transferase function in the biochemistry lab.  Khristopher presented this work with Krystal Scinto at the 2015 Sacred Heart University Academic Festival.

Prior to graduating, Khristopher worked as a Science World Reporting intern at Scholastic Corporation.

JOSEPH WETHERELL

B.S. Chemistry, B.S. Molecular and Cellular Biology, 2015

Joe worked to establish the yeast two-hybrid system for use in the lab for identification of conserved interactions of fission yeast Sir2. He received travel funding from the College of Arts and Sciences Undergraduate Research Initiative to present this work as a poster at the 2014 National Meeting of the American Chemical Society in Dallas TX. Joe also presented his work at the 2014 Sacred Heart ​University Academic Festival.

After graduating, Joe enrolled in Quinnipiac University Medical School (Hamden CT).

MODI ALMUTAIRI

M.S. Chemistry December 2014

Thesis: Sir2 function in genome integrity

After graduating, Modi accepted a position as a high school science teacher in Jedda, Saudi Arabia.

NAJWA ALJEHANI

M.S. Chemistry, August 2014

Thesis: Targeted control of gene expression by the Sir2 histone deacetylase

After graduating, Najwa accepted a position as a lecturer at Qassim University, Buraydah, Saudi Arabia

©2018

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